At first, when they had just met, he didn't love her and kept hurting her. Later, when he finally developed some feelings for her, Catherine appeared, and then there was the divorce and the shipwreck. He thought that after their reunion, he could finally love her properly and make it up to her, but instead, she was dragged into the conflict between him and Wooden Drucker because of him.
When he finally had the chance to bring Wooden Drucker to justice, he got hurt again, and this time it was so serious. Being a doctor, he had a general sense of how badly he was injured.
How could someone as gentle and fragile as her endure all this pain? Thinking of the suffering she had been through, his heart ached, filled with remorse, guilt, and various complex emotions that overwhelmed him. He felt like he owed her... so much.
He wanted to apologize to her but couldn't bear to wake her. So, he just held her hand tightly, lying there quietly, waiting for her to wake up.