Looking at the initial situation, the story of "Blood of Lies" erupts with three disasters, which at first do not appear to have too much connection.
They are, specifically, earthquakes, Beastification Disease, and a doll rebellion.
Violent earthquakes directly destroyed both the internal and external transportation systems of Charlton City, not only causing many buildings within the city to collapse and blocking the roads but also severely damaging the bridges, cable cars, and tunnels that connected the city to the outside, resulting in its complete isolation and turning it into a lone city.
However, the damage to the city from the earthquake was the least of its concerns.