Ryoto Yuuki: An older brother of Rito and Mikan. He is also Lala's fiance. His hair is short and black. He has his eyes closed the whole time unless he is with someone who knows about them. He is about 1.70m tall and is pretty muscular. He is someone who doesn't care about his reputation, but if his reputation caused problems for someone he cares about, he would change. He can mask his own emotion with ease, and it's hard for even his family to see through his mask. He is adopted, but only he and his parents know about it. He is terrible at reading the air, but it's not something you would notice at first sight. In middle school, he was on confessing spread but was rejected every single time except one time...
Rito Yuuki: The middle child of Yuuki family. He doesn't have much contact with the opposite gender, so they easily embarrass him. He has a big crush on his classmate Haruna Sairenji. He is very good at football but stopped playing in middle school to stay with his siblings at home since their parents are often away. He has terrible luck as every time he tries to confess something, or someone interrupts him.
Mikan Yuuki: The youngest of the Yuuki family but, on the contrary, the most mature. She takes care of the house. She is very perceptive for her age and worries the most about her oldest brother as she can't tell when he doesn't like to share what's on his mind. She doesn't want to be treated like a child.
Lala Satalin Deviluke: First princess of Planet Deviluke. She ran away from home because she wanted to be the one to choose the one she marries, and so she did after coming on Earth. She can be considered childish as she is always excited about the smallest of things. Despite her naturally cheerful and somewhat innocent nature, Lala is not as emotionally immature as she would appear. On rare occasions, she shows that she can be impish as well, but that trait is shown only to Ryoto as of now. She is also a genius inventor who built countless machines, but most were used to prank other people.
Peke: One of Lala's inventions. He can turn into any desired clothing.
Haruna Sairenji: Classmate to both Rito and Ryoto. She is a member of the tennis club. She has a crush on Rito because of his kindness and is friends with Lala. Haruna is scared of ghosts or anything supernatural to a scary degree.
Yui Kotegawa: She is the head of the school disciplinary committee. She has great hatred towards men and has little tolerance for anything she doesn't deem as 'acceptable behavior'.
Risa Momioka: Classmate of Ryoto and friend of Haruna and Mio. She is very fun-loving, mischievous, and perverted. She enjoys teasing shy people, but after finding challenge in Ryoto, she tries to break his calm mask, but as of now, she is unsuccessful.
Mio Sawada: Friend of Haruna and Risa. She is also perverted and often helps Risa with her pranks.
Kenichi Saruyama: He is Rito's best friend and a huge pervert.
Ryouko Mikado: An alien doctor who works as a school nurse. She is one of the few people who knows about Ryoto's eyes as she helped him test them in a safe environment.
Principal: A pervert who runs the school and allows cute girls to enroll in it.
Saki Tenjouin: She is the arrogant self-proclaimed queen bee of the school. Saki is one year older than the main cast. She is wealthy, and it shows in her behavior. While she is not a bad person by nature, she can be annoying to others how she thinks she's better than the 'commoners'.
Rin Kujou: Saki's bodyguard and classmate. She's known Saki since they were very young, and even then, her role was the same. She practices kendo and is often seen carrying a shinai.
Aya Fujisaki: She was saved by Saki and Rin from the bullies, and from that day, she's started following them, becoming a part of their group.
Ren Elsie Jewelria: He is the childhood friend of Lala, and he has a crush on her. He wanted to become more manly because of the promise he made with Lala. He recognizes Ryoto as the manliest of men and calls him Aniki. He wishes to learn from him how to be a real man.
Akiho Sairenji: Haruna's older sister. She is currently attending college but is also working at the side. She knew Ryoto during his middle school phase. Akiho is an airhead but can be mature if the situation needs it.
Kyouko Kirisaki: A famous idol, best known for her role as Magical Kyouko, the fictional magical girl character, and star of her television series, which Lala loves watching. She is kind, modest, friendly, and hates perverts. Her fans are very enthusiastic.
Shizu Muramase: Shizu also known as Ohishizu is a ghost of 16 years old girl who died 400 years ago. The cause of her death is currently unknown. Oshizu has long blue-violet hair and irises. In her ghost form, she wears a white kimono and purple sash, she also has light-colored wisps floating around her. She is sincere, kind, and very curious about the modern world and has a severe case of cynophobia (fear of dogs).
Jugemu: His full name is Jugemu Jugemu Go-Kō-no-Surikire Kaijari-suigyo no Suigyō-matsu Unrai-matsu Fūrai-matsu Kū-Neru Tokoro ni Sumu Tokoro Yaburakōji no Burakōji Paipo Paipo Paipo no Shūringan Shūringan no Gūrindai Gūrindai no Ponpokopii no Ponpokonaa no Chōkyūmei no Chōsuke but everyone around him call him Jugemu. He is an alien that came to Earth to 'take care' of Ryoto. He is a fish person and wields dual swords that can shoot out compressed water. Usually, he wears black glasses because he can't use his eyes on the land, however, he doesn't have any problem navigating around thanks to being incredibly sensitive to moisture in the air. Jugemu is incredibly naive and optimistic and while he may look scary he is harmless. He works so he can send money to his family.
Zastin: Zastin is Lala's personal bodyguard and the best swordsman on Deviluke. He is also the commander of Planet Deviluke's royal family bodyguards. He discovered his new passion for making manga after being an assistant to Saibai Yuuki, Ryoto's dad. Right now he is making manga together with Ryoto called 'The Spectacular Spiderman'. Zastin has greyish hair and blue eyes and is quite formal with those around him.
Koro-sensei: "Korosensei acts as the homeroom teacher of Class 3-E of Kunugigaoka Junior High School. He claimed to be responsible for creating the permanent crescent moon and added that he planned to destroy the earth after teaching Class 3-E for a year. Korosensei has the appearance of a yellow octopus. He is about three meters tall and possessed a large, bulbous head with a large smile that rarely breaks or moves and small, beady eyes. He is training Ryoto not only on how to use his powers but also other useful things.
Kaede Kayano: Kayano is a short girl with light green hair that is always fashioned in unique cat ear-styled pigtails. She is also incredibly flat in other words her breasts are nonexistent. Kayano is one of the most kind, cheerful, and passive members of the class who frequently acts as support in assassination attempts with her ability to assess the situation and adapt herself to them. That however is a lie created by herself.
Rio Nakamura: Rio has long straight strawberry blonde hair that is parted in the middle and worn swept behind her shoulders, and aqua blue eyes with notably long eyelashes. Rio is also a friendly, energetic girl and somewhat of a trickster. She was one of the few who wasn't scared to get closer to Ryoto after he snapped. She was even more interested in him after that event.
Karma Akabane: Karma has pale skin, short red hair, and pale sharp eyes. Behind his usual innocent-looking, smiling face hides a torturous and rather sadistic personality. Karma is well-known throughout the school for his violent behavior and troublesome attitude. He is quite cunning, mischievous, and somewhat sadistic, usually playing foul, tricking, and at times manipulating, humiliating, and fighting others. He got closer to Ryoto after they did pranks on each other and earned their mutual respect. He isn't scared of Ryoto's strength in the slightest and has numerous blackmail materials ready to be used.
Nagisa Shiota: Nagisa is a petite-framed boy with blue hair and azure eyes. He is easily mistaken for a girl because of that and his shoulder-length hair. He is a natural-born assassin and best friend of Karma.
Tadaomi Karasuma: Tadaomi Karasuma is an agent sent from Japan's Ministry of Defense to supervise Korosensei. He is very serious most of the time but he learned to enjoy teaching the class over time. He is often a victim of Ryoto's notorious bets. He teaches the class PE.
Irina Jelavić: Irina is a tall and beautiful fair-skinned young woman with wavy hip-length light blond hair that is split on either side, large light blue eyes, and a curvy body type that she can utilize to seduce and manipulate her assassination targets in order to achieve her goal. Unfortunately for her Ryoto chose her to be his lollipops supplier after she lost a bet against him. Her nickname in class is Bitch-sensei and she teaches English with 'unconventional' methods.
Ritsu: Is an AI created to kill Koro-sensei but she gained a free will of her own and started helping the class with it instead. She can move from one device to another thanks to a wireless connection.
Sophia: Karen's older sister and powerful entity on her own. For some reason, Karen hates her even though Sophia behaves like a regular airhead. She likes teaching and loves her little sister. She wants everyone to call her Onee-san. Karen claims that Sophia is perfect in everything she does. Sophia looks in he really 20s and possesses long wavy light blue hair. Her eyes have small stars inside them and looked like a galaxy to anyone who saw them.