After Han Li reached mid Core Formation stage, he had remained in seclusion for an additional twenty years. During this time, he still hadn't exhausted all of his medicine pills and carried about a smaller portion of them in his storage pouch.
His early departure from seclusion without having yet consumed all of his medicine pills was due to neither restlessness nor impatience. It was because he had encountered a bottleneck as he neared late Core Formation stage. Until he broke through the obstruction, his cultivation wouldn't progress in the slightest even if he used more medicine pills.
These breakthroughs were left completely up to destiny or fortunate encounters. There were absolutely no established methods to break through such a bottleneck. However, in the past, cultivators had managed to break through this stage through merely cultivating, touring the world, or battling in a life or death struggle. Each occurrence was entirely unexpected.