The death of the First Born's brain was confirmed to be irreversible, and this was good and bad news at the same time. The good news was, they did not need to worry about the First Born suddenly waking up and wrecking the surviving Executor civilization again. The bad news was that Hao Ren would not be able to "cure" the First Born enough to recover its senses. That was one of Hao Ren's initial plans: discover the ailing brain core, then find a way to cure it. If the First Born had not totally fallen into madness, perhaps it could have been cured? As it was, trying to completely kill this mythological creature that had already fused with the planet was extremely difficult. It was almost equivalent to destroying the planet altogether.
Hao Ren had to abandon that plan... The patient's brain was a goner...