This is especially clear in the fact that most of the people working in the human farms are amplifiers and nulls. They can be taken out with a gun. They are not that dangerous. But they have offended the police force several times.
The only one truly dangerous among them is a weapon-class super who is their boss. This woman has rigged everywhere in the building with turrets.
The amplification she receives from her numerous subordinates has enhanced her to the point that the building has become a death trap. Anyone that enters must be able to weather through a literal hail of flying ammunition.
What raised the difficulty of the mission further is that guns can't be used to fight her because she can control guns. So anyone who wants to take her down must do so with only their abilities.