After hearing what Gwen said, Lucifer realized what was going on, and he was glad that Gwen didn't know about his affairs with his mother, Jennifer, and Ashley.
He felt relieved at the thought that his secret was still safe, but he also knew that he couldn't tell Gwen about it because if an on-screen kiss could make her angry like this, then she would never forgive him if she knew the truth.
'I don't want to lose her... But I also can't tell her the truth... Damn it, what should I do? What can I do?
If I lie to her now, there's no turning back. But if I tell her the truth, then I might lose her forever too. She'll never forgive me for cheating on her with my mother, and I won't be able to blame her for that. It's just not fair...
Why did I have to fall in love with my mom? Why did she have to fall in love with me? And why did I have to go after Aunt Jennifer, Ashley, and Rose too? Why did they have to come after me as well?