As for the abundance of extraterrestrial creatures... that's even easier to understand.
After all, the Alchemy small world continent isn't like Earth with single intelligent human life; instead, it's inhabited by multiple intelligent species. And where have they now arrived?
In the void!
On the battlefield of gods and demons!
The variety of species here is definitely far greater than in the Alchemy small world; this is simply to be expected.
Therefore, there's no need for humans to come up with explanations; they've already inferred a completely logical connection in their minds.
The key to the Alchemy small world's end-of-world catastrophe is a life alchemist named Wan Ke, who created the Philosopher's Stone, causing the ancient alchemy array that sealed the small world to break. This allowed their kin in the void to perceive the existence of the Alchemy small world.