Without a doubt, the so-called "curse" is but a foolish utterance.
For Seti, Naifertali was the only exceptional one.
Though Naifertali possessed the talent of a Transcendent, she chose not to follow that path. She believed that merely by the virtue of "being apprenticed to a Bone Healer," coupled with the mystical knowledge imparted to her and her intelligent mind, Naifertali could easily gain the right to "refuse."
In other words, by the time she "graduated," her wish was already within her grasp.
Her senior apprentices felt the same way.
According to the original contract, Seti was responsible for providing them with an education; once they felt they could realize their wishes, they were to leave the Bone-nurturing Ground. After they believed they had achieved their wishes, they were to return to their teacher's side, to recount the stories of what had happened to them after they had left.
This was a ritual established by Seti.