Michael Wilson (formerly Jonathan Anderson) - Spider-Man: Michael is the main protagonist, continuing his role as Spider-Man and protecting the citizens of New York City from crime. While facing personal and professional challenges, he remains the central focus of the story.
Captain Edward Wilson: Edward is a dedicated police officer and a supporting protagonist, collaborating with Spider-Man and other law enforcement agencies to combat crime effectively. He provides crucial support and assistance to Michael in his crime-fighting efforts.
Mark Fletcher - Nightwing: Mark is another supporting protagonist, Michael's Best friend and working closely with Spider-Man as a crime fighter. He has matured over the years, refining his combat abilities and expanding his role in keeping the city safe.
Loe Halloway (formerly Loe Smith) - Angel: Loe, now part of the Halloway family, is a supporting protagonist who continues his vigilante activities as Angel. He has grown both personally and as a crime fighter, using his enhanced abilities to aid Spider-Man and his allies.
Emily Hawkins: Emily is a supportive partner to Mark and a supporting protagonist in her own right. She provides encouragement and understanding to Mark as he continues his crime-fighting endeavors, playing a significant role in his life.
Mary Fletcher: Mary is a supporting protagonist and Mark's sister and Michael's girlfriend, offering him love and support as he navigates his responsibilities as Spider-Man. Their relationship has deepened over the years, with Mary understanding the challenges Michael faces as a superhero. She have vibrant personality with red-violet hair.
Chris Hilton: Chris is a loyal friend to Michael and a supporting protagonist who provides moral support and friendship as they face various challenges together. He stands by Michael's side throughout their adventures