After that simulation,Itsuke has complete knowledge of medicine and by slightly influenced by stimulation,itsuke wants to reasearch on healing and strengthning practices that helpful to body andnow he wants to creates a pill that can heal soul master using ordinary plant species like grass,tree leaves,normal roots of plants and other ordinary normal daily life vegetables.
Itsuke started his reasearch and created a pill using bluesilvergrass and using extraction of vitality in bluesilvergrass,the vitality heals the normal people but cannot heal the soul master so Itsuke further research on bluesilvergrass and vitality containing plant species and create a medicinal pill that heal soul master up to level 39.
And he also created several other pills for body strengthening, vitality strengthening, muscle strengthening and soul power increasing pills and all these pills can only taken three times in their life up to level 40 spirit powerbacuse these pills only useful under level 40spiritual power.
After the five years of simulation,he concludes that stimulation has influence on him and it can go away eventually and some of habits in simulation effects him and after some time that effect go away,so he only stimulate once a month and cultivate stimulation opportunity to system points.
After the reasearch, Itsuke also created pills that helpful up to the level of perreles douluo and continues practising .