The prolonged separation of soul and body.
Or the long-term severing of the soul from the Transcendent State.
This would make the body gradually uncontrollable, easily killed by others, or even captured.
At the same time, prolonged imprisonment by [Destiny Fang] would warp and change the soul's self-will.
Turning the soul into a slave subservient to [Destiny Fang].
Eventually becoming a part of that twisted pattern of [Destiny Fang].
These are the prices paid for unimaginably prolonged longevity.
Even... you may not get to enjoy the benefits of a prolonged life and have to check into [Destiny Fang] prematurely.
When Tuck got [Destiny Fang] and felt it carefully.
He gradually understood the many unseen conditions and constraints involved.
"If... I could live to be 500 years old and use this [Destiny Fang] to prolong my life when I'm about to die, it seems... that would be the right way to use it."
"Anyway, I'm almost dead, so switching rooms for the soul isn't too bad."