Someone would need to be in the lower realms; otherwise, there would be no use. A higher realm cultivator already had their body constitution changed completely.
Changing it again using a method like this would result in a huge backlash that could even end in their death.
Here is the passage with grammar corrected and changed to past tense, as per your instructions:
And this death was not just of the body. Since there was the beast's lingering will, there was a possibility for them to completely die.
'If I mix some of this bloodline into Pi, the result will be good. I can just use progenitor aura to subdue the lingering will here.'
As Pi's body was made by him, Alex could modify it to support this bloodline.
He also wondered what would happen if he mixed two bloodlines; theoretically, some part of it would conflict, but if he could filter it, combining the bloodlines should not be a problem.
Basically, it manipulates the creature's DNA.