Shane knew about the Quick Learner talent as he had a chance of obtaining it before when he had looted them from Survivor Zombies.
However, the Quick Learner Talent that he had encountered was either Common or Uncommon grade only.
Needless to say, that level of talent was nothing in his eyes, considering his current set of talents.
Anyway, this Quick Leader Talent allowed Lysandra to obtain a skill called Assassin's Breath. This Survivor Skill made her breathing different from other Survivors to hide her presence. This was the reason why Cloud needed a few more seconds compared to others in order to sense her presence.