Kiara first met Yuzo Joel when she went to eat at a Private Restaurant with him, where Yuzo Joel, disguised as a chef, gave Kiara a jar of wine; he already had plans to approach Kiara and make a good impression.
According to Professor Liu Taylor, during the second meeting Mario Yuno was not present, but he'd heard from Kiara that she once encountered Yuzo Joel at the Psychiatric Hospital—this was the deliberate arrangement that Professor Liu Taylor spoke of.
From then on, Aka was assigned to protect Kiara at all times, and Yuzo Joel appeared repeatedly.
This just proved the saying, "One begets two, two begets three, three begets everything." After the third meeting, it led to the ensuing series of events.
Mario Yuno's brain structure was somewhat unique compared to others; he had an extraordinary ability to piece together details and clues. He quickly assembled a picture, and the truth seemed on the verge of revealing itself.