Yknow, the Spot has one hell of a power. I mean, multiversal travel, portal creating, absorbing dark matter from alchemax facilities to gain even more power. Makes me wonder what the limit is.
I personally think making a character have his power is a pretty good idea. The huge downside is the appearance of the Spot, which doesn't really allow for "normal" human interactions (go for it if you want to but I'd tune his appearance to maybe make it more human-like)
Update: I just realizes that the spot is technically human made (even if it was made in an alchemax facility). This can be a goal for a powerless character maybe. In the comics the Spot also has the ability to concentrate all of the spots he has into one and gain his original appearance back, which solves the problem above (Into the Spider-verse's Spot seems to not have that ability, which kind of makes him unique, but in the later comics the Spot's appearance jumps from being a costume to not being one all the time so I don't think this matters that much)
One Idea is to make him a MHA character, considering he would definetly fit right in. It also might work as a fusion nomu combining the quirk "Warp Gate" with something else.
Honestly the part after the Spot got betrayed and went insane in his spotted dimension is really cool. Using his spots as a way to quickly assasinate people by snapping their necks, strangling them, etc. Also did I mention that he comes back from death in the spotted dimension? (even if it's just one line in the comics) I have no Idea if it's cannon or not but he always seems to come back after dying a lot of times in the comics (I have not read the comics but watched a video so take this with a grain of salt).
[Out of topic]
Yeah so I might be running out of ideas so don't expect regular updates from me.