Harker was reminded by a certain someone when he got called 'friend' by this imposter.
There was just something unique about the way Ivan Ivanovich would call people his 'friend', with all the realness and affectionate tone of a true friend would, yet at the same time feel so fake.
And Harker knew he must have adapted it from the fake people he had been around the Circus Cabaret. Those 'people' who would laugh and cry but never actually felt anything. Just a bunch of hollow mannequins.
Seeing this mannequin wear such a similar face yet a completely different demeanor up close in person….. It produced a more visceral effect on him that he expected.
He thought that after all the business with a cannibalistic pedophilic priest taking over his mother's body, or his clone occupying his friend's body and pretending to be him, or even a Native American man he thought to be his friend being part of some flesh hive all along would have prepared him for this.