The reversible environmental factors are dietary habits, sedentary lifestyle and professional and non-professional work overload and stress. Whereas the irreversible environmental factors are age, gender, genetics, degenerative process of evolution of mind and fibrotic changes after any traumatic injury to brain involving gray matter or white matter. The professional proficiency and prosperity requires highly regulated and modulated strenuous mental workout to reach the acme of such excellence and finesse resembling elitist status quo class of intuitive cognizance and logical conscience where any intellectual can go beyond the limits of influence of artificial intelligence. These environmental factors play a pivotal role in the successful progress of genetic-based intelligence and artificial intelligence taking advantage of its subliminal E-messages for the betterment of whole humankind. The humanity at large is positively promoting the reality of existential intelligence out of no mind.