While nothing extraordinary happened when the void mana interacted with the natural mana in the atmosphere, Toz realized how the void magic broke down magic. Since magic relied on the mana it was composed of, the magic would destabilize and collapse if that mana mixed with mana of other attributes that the mage didn't have control over.
Even if the void magic mixed the mage's magic with another attribute that the mage had, it would still collapse. The mage wouldn't be prepared for the abrupt change in the structure of mana. The mage also wouldn't be able to control the mixed mana since they won't have any experience with blending two different elements so intricately.