Juyuan Powder, the elixir, has the largest circulation on the market.
No matter what realm a martial artist is in, they need a lot of Juyuan Powder. If you want to cultivate slightly faster than others, you can't do without it.
However, taking too many elixirs may cause a buildup of toxins and form Dan poison, so you can't keep taking elixirs all the time.
There is another type of elixir called Condensed Frost Pills which are specifically designed to eliminate side effects and detoxify Dan poison. They also sell quite well.
Though taking medicines frequently in between may be troublesome, there are two criteria for good Juyuan Powder: one is that it provides enough accumulation of Star Power, and the other is that it has minimal side effects.
If these two criteria are met, that would be considered a good elixir.