This paper by Lu Li made him stand out in academia and made him a hot star in University. In addition, some companies contacted him, thinking that this technology has not yet shown value. Acquire the patent in his hand at a lower price.
However, it can only reach this level. After all, this technology is too far away for ordinary people, everyone will not pay attention to it, and the media is not too interested, unless Lu Li uses this technology to overcome AIDS. The world's five terminal illnesses, such as cancer and cancer, have aroused widespread concern.
At this time, Lu Li is planning to do so. The single-base gene editing technology is just a small test. He has targeted AIDS, cancer and other terminal diseases.
These terminal illnesses that make people feel terrified are difficult to cure with traditional medical methods.
But it can be cured by gene therapy technology.
The single-base gene editing technology is an "ideal" tool for gene therapy technology.
The target gene can be edited accurately.
University, library, study room.
Lu Li finished reading "The Pathogenesis of AIDS", then placed it on the thick stack of books on the right hand side, picked up "The Mystery of the Human Immune System" from the left hand side, and looked through it attentively.
After watching for a while, his eyes suddenly lit up.
"The macrophages of the human body are soldiers of the immune system. They patrol the body unswervingly for 24 hours and can swallow bacteria, viruses, cancer cells, and other pathogens."
"However, macrophages are not able to fight HIV and have become a dish for HIV."
"If I modify the genes of the macrophages so that the macrophages can kill HIV, and can also identify those cells infected by HIV, and swallow those infected cells and destroy them, won't I be able to conquer AIDS? ?"
"For ordinary scientists, this is very difficult to do because they still don't know much about the behavior of HIV after entering macrophages, and they don't know why macrophages can't beat HIV."
"For me, this is a highly feasible solution. I can completely control the macrophages in my body, let it eat HIV, and then figure out why it can't beat HIV, and make targeted changes. The genes of phages."
"Next, modify the genes of the macrophage so that it can recognize the cells infected by HIV and swallow those cells and destroy them."
"If it succeeds, I just need to replicate the entire process in the lab."
"Yes, just do it."
Lu Li raised his head excitedly, put the books on the table away, and prepared to return these books first, before looking for HIV.
Ordinary people can't avoid HIV, but Lu Li is not afraid of it. He can perfectly control every cell in his body and perform atomic-level operations on any substance in the cell.
No matter how awesome the HIV virus is, it is also made up of molecules, and molecules are made up of atoms.
Can Lu Li directly decompose HIV into atoms, but should he still be afraid of HIV?
Even if it is a virus more powerful than HIV, as long as it enters Lu Li's body, he is a younger brother.
Of course, he has nothing to do with the viruses in other people's bodies.
However, at this moment, Lu Li found that as he stood up, more than half of the people in the whole study room cast their enthusiastic eyes on them. Well, these people are all girls.
The fiery gaze in their eyes wanted to melt Lu Li.
Lu Li is also a little helpless.
Since he became a celebrity of University, he has gained titles such as "School Grass of University", "The Strongest Academic Tyrant", and "Legendary Freshman". He has a large number of female fans who want to attack him.
No matter where he goes, he is the focus of everyone, and he is often approached by his sister.
This made Senior Sister Qin Wei nervous, for fear that he would be fascinated by some fox.
Every time he comes to the library, Senior Sister Qin Wei is with him.
Now, Senior Sister Qin Wei is by his side, and she also stands up, looking murderously at the girls who want to attack Lu Li.
I didn't even taste the soup, you just want to start.
Humph, there is a kind of letting go.
Lu Li shrugged, walked out of the study room with a stack of books, and returned the books first, and then left the library with the senior sister.
She was about to say goodbye to her senior sister. Unexpectedly, the senior sister received a phone call from her roommate quietly. Jingjing and her boyfriend wanted to make a dinner with Lu Li.
Lu Li didn't refuse. To talk about feelings, he must integrate into each other's circle.
Lu Li and Qin Wei came to the school parking lot while talking and laughing. From a distance, they saw a sweet girl in a pink princess dress, waving to them at the side of a BMW. Next to the girl, there was another girl wearing a dress. Young man in white shirt.
Qin Wei introduced that the girl is her roommate Zhou Jingjing, and the young man is Zhou Jingjing's boyfriend Wang Hao, a rich second-generation.
"Weiwei." Zhou Jingjing took Qin Wei's hand, looked at Lu Li with interest, and said with a smile: "Lu Xiaoge, I finally saw you with my own eyes. It's more handsome than the picture. No wonder Fairy Qin is also Moved for you."
At this time, Wang Hao, who was standing aside, saw his girlfriend talking to Lu Li with a smile, and was a little bit savage. He took the initiative to step forward and greet Lu Li: "Hello, I am the quiet boyfriend Wang Hao. "
As he spoke, he glanced at Lu Li roughly. He looked like a student, and the total amount of clothes on his body would not exceed 1,000 yuan.
He immediately felt a sense of superiority in his heart. What if you are talented, at most you will be a professor or researcher. The money earned in a year is probably not as much as my pocket money, and I am not a person in the same world.
Of course, he just thought about it in his heart, and would not expose these thoughts.
On the surface, he is very enthusiastic.
In the world, there are many such people, who are enthusiastic on the surface, but despise you in their hearts.
At this moment, a red Ferrari supercar drove from a distance and stopped beside Lu Li.
After the flame is turned off.
The beauty in the driving position got out of the car, her legs were slender and slender, and her figure was perfectly set off by a tight dress, and the faint fragrance of perfume came to her face even more.
She took off the silver-white goggles, walked to Lu Li's side, and said softly, "Mr. Lu, get acquainted. My name is Xia Gang, the vice president of Xia's Pharmaceuticals. I was about to go to the University Library to find you. Are you interested in having a meal together?"
As she spoke, she fluffed her hair, and a faint perfume smell came over her face.
Extraordinarily attractive.
To be honest, Lu Li is a little attracted, as a man, even if he has a girlfriend, seeing a beautiful girl will be heart-warming.
However, there is only a slight movement, Lu Li is not the kind of person who can't walk when seeing a beautiful girl.
What's more, Senior Sister Qin Wei is still by her side.
He shook his head slightly and said, "You don't need to eat, just tell me if you have anything."
A strange look flashed in Xia Gang's eyes. She knew her charm, especially for a seventeen or eighteen-year-old boy like Lu Li. Faintly agreed to her various requests.
But Lu Li was hardly affected by her.
It seems that Lu Li cannot be treated as an ordinary boy.
Xia Gang's flames and red lips lightly opened: "Then I will tell you the truth, our company wants to buy the patent for the single-base gene editing technology you have, 100 million soft sister coins."
100 million!
Hearing this number, Wang Hao, who had a strong sense of superiority towards Lu Li just now, widened his eyes!
This is 100 million!
Already equivalent to his family's assets!
Zhou Jingjing also looked at Lu Li with bright eyes. For just a patent, she can sell for a sky-high price of 100 million. She is handsome and is the ideal boyfriend. If she hadn't had a good relationship with Qin Wei, she would have Want to win love with a sword.
Qin Wei was also a little stunned. While being happy for Lu Li, there was also a heavy pressure. The younger brother is growing too fast. Can I keep up with him?
Lu Li smiled faintly: "Sorry, I don't have the idea of selling patents. If your company wants to obtain patent authorization, you can talk about it."
Single-base gene editing technology is very important to him.
If he wants to overcome terminal diseases such as AIDS and cancer, he needs this technology.
How could he sell patents?
What's more, the value of the patent for this technology is far more than 100 million soft sister coins.
At the very least, it has to be over several dozen times.
Of course, that is the patent fee that can be received during the validity period of the patent, and it is not a one-time payment.
Xia Gang was silent for a moment, she had already seen that Lu Li is a very assertive person, it is difficult for her to change Lu Li's attitude.
"It seems that this time it should not achieve the purpose I wanted."
Xia Gang sighed in her heart, but still kept a smile on her face, and said softly; "That's really a pity. As for the issue of patent authorization, we will talk about it later. Let's talk about another matter first. I want to invite Mr. Lu to our Xia family. As the chief scientist at the Pharmaceutical Research Center under the pharmaceutical company, as long as you agree, you can get 1% of Xia's shares. If you perform well, you can also get more share awards."
Hearing Xia Fang's words, Wang Hao and others were shocked again. The scale of Xia's Pharmaceuticals is not small. It is a large group with a market value of tens of billions. They actually took the initiative to invite Lu Li, an 18-year-old young man, to be the chief scientist, and as long as he agreed, You can get 1% of the shares, which is several hundred million.
Is Lu Li worth the price Xia's Pharmaceuticals paid so much?
If they ask Xia Gang, Xia Gang will definitely say: It's worth it.
Because Xia Gang has investigated Lu Li in detail and determined that Lu Li is a rare genius in the world. It was after the college entrance examination that he really started to study biology. As for junior high school biology and high school biology, they are just basic things and can be ignored.
From studying biology to researching the single-base gene editing technology that shocked the academic world, Lu Li only took two weeks.
In addition, Lu Li's mentor, Professor Xu, an academician of the Chinese Academy of Sciences, has also repeatedly expressed his appreciation for Lu Li and mentioned that Lu Li's biological attainments are no worse than him.
This shows how terrifying Lu Li's talent is!
The most important thing is that there are many problems in current medicine, such as cancer, AIDS, etc. These diseases can hardly be cured with traditional medicine. The only hope is gene therapy.
And Lu Li, being able to research single-base gene technology, shows that his knowledge in gene technology is already the world's top. Coupled with his terrifying talent, Xia Gang can conclude that if someone can use genes Technology overcomes cancer, AIDS, etc., then… this person must be Lu Li.
Therefore, if Lu Li can join Xia's Pharmaceuticals, Xia's Pharmaceuticals may take off and become a global pharmaceutical giant.
Therefore, she is willing to use 1% of Xia's shares to solicit Lu Li. If Lu Li achieves results, even if it is 10% of the shares, or even 20% of the shares, she is willing to take it out.
However, faced with the "sky price" offered by Xia Gang, Lu Li refused without even thinking about it: "Sorry, I don't have this idea. Thank you for your company's kindness."
He didn't want to be recruited, even if the other party paid a high price.
Xia Gang was not too surprised. After Lu Li's request to acquire a patent was rejected, she had a hunch that Lu Li would also reject the position of chief scientist at Xia's Pharmaceuticals.
"That's really a pity." Xia Gang still smiled, "I won't bother you today, I wish you a good time."
After speaking, she gave Lu Li a meaningful look, then quietly returned to the sports car, started the car and left.
When the car left Lu Li's sight, she sighed softly: "Due to insufficient preparation, this contact completely failed, but… the first meeting is considered a acquaintance, the next meeting, I will be ready."*
After such an incident, Wang Hao's attitude towards Lu Li changed drastically. After eating seafood at the Meiyuan Hotel, he originally planned to take Zhou Jingjing to go skiing with him.
However, at this moment, Lu Li received a call from Professor Xu. Professor Xu asked Lu Li to go back to school. Wang Hao immediately expressed enthusiasm that he would send Lu Li and Qin Wei back to University.
If it was before, Wang Hao would certainly not be so enthusiastic. If you are in a hurry, take a taxi by yourself.
But now, Wang Hao has determined that Lu Li has a promising future, and of course he needs to make friends with his heart.
After returning to University, Lu Li went directly to Professor Xu's office.
Qin Wei and Zhou Jingjing went back to the dormitory together.
"Weiwei, this little boyfriend of yours is amazing. If it wasn't for you to have a good relationship, I would have to attack him, so you have to hurry up and look at him, don't let him be strayed by any fox. "
Zhou Jingjing said.
"I didn't expect him to grow up so fast and so popular." Qin Wei said that Yali Mountain is big, "and I can't help him. When I'm with him, he always has the initiative."
"Then there is only a trick, you find a chance, take him down, and crush him severely."
Zhou Jingjing offered a plan.
"Take it down? Suppress?"
Qin Wei was a little puzzled.
"Mom, you don't even understand this, it's simply terrible…There is no way, when I return to the dormitory, I will give you the resources I treasured in the hard drive, so that you can see the world."
Zhou Jingjing said mysteriously.
…
After Lu Li came to Professor Xu's office, he found that besides Professor Xu, there was also an elderly man with gray hair.
"Xiao Lu, let me introduce to you."
Professor Xu looked at the old man and said with a smile: "This is Professor Tian Zhixing, an academician of the Academy of Sciences, and a world-renowned expert in biovirology. Aren't you studying HIV? I'm not familiar with this field. I can't help you. , So introduce you to Professor Tian. If you have any virus-related questions, you can consult Professor Tian or ask him for help."
Hearing what Professor Xu said, Lu Li was very moved. He was studying HIV. Professor Xu took the initiative to introduce him to Professor Tian, an expert in biovirology.
"Teacher, thank you."
Lu Li solemnly thanked Professor Xu for his friendship, he will keep it in his heart.
Immediately, he looked at Professor Tian again.
In fact, he had heard of Professor Tian's name a long time ago.
Professor Tian is the country's top biovirology expert. He studied in Star Country in his early years, and Star Country wanted to retain him with very generous terms. As for his contribution… There is a saying in academic circles that Professor Tian holds up half of the sky in virology at University.
"Professor Tian, I will trouble you in the future."
Lu Li is also not hypocritical. Since Professor Tian is here, it means that he is willing to help himself.
"No problems, no problems at all." Professor Tian said: "Now the shape of the global disease is becoming more and more serious. Large-scale epidemics have occurred many times. Therefore, I have always hoped that there would be more. Talented people to join the field of biotechnology, only with cutting-edge technology, the world can be calm in the face of major diseases and epidemics".
"The AIDS you are studying is also a disease that gives me a headache. In just a few decades, there has been an explosive growth in the world. There are already millions of patients, and the more young people are now The more open it is, the epidemic of AIDS may become more serious in the future."
Speaking of this, Professor Tian couldn't help but sigh. The phenomenon of AIDS among young people is really heartbroken.
Invisibly, Lu Li was also infected by Professor Tian's feelings of worrying about the world and the people, and his heart couldn't help but his respect and admiration for Professor Tian surged.
Professor Tian continued: "Xiao Lu, I have already read your information. To be honest, you are the most talented scientific researcher I have ever seen. As long as you don't waste your talents, you will surely become It's the pillar our biological community in the future. So I'll try my best to help you. You can come to me for anything you have, whether it's scientific research or life."
"Thank you Professor Tian."
Lu Li's heart is also a little touched. He can see that Professor Tian is willing to help him, not for fame, nor for financial benefits This kind of sentiment, now those who believe in the supremacy of money People are hard to understand.
After a pause, Lu Li said: "Actually, I already have ideas about treating AIDS. I want to use single-base gene editing technology to modify the genes of macrophages so that macrophages can recognize and eliminate HIV. At the same time, it can also identify and eliminate cells infected by HIV."
After listening to Lu Li's words, Professor Tian thought for a while and said: "This is indeed a way of thinking, but it's a bit more difficult, because we don't know enough about the genes of macrophages, and we are also aware of the behavior of HIV after entering macrophages. I don't know much, and the current gene editing technology is not precise enough, and the possibility of off-target is very high. When modifying the gene, a little failure may not be allowed, because it may bring unexpected negative effects. "
Having said that, Professor Tian seemed to have thought of something, and said with a smile: "I am so confused that I forgot the single-base gene editing technology you developed. This technology is highly accurate and is used for gene editing. If it is, the success rate is very high…Moreover, if you can develop this technology, it shows that you have a good understanding of genes…Xiao Lu, I support you to explore this path, science, it is to continue to explore and try. Only then will it be possible to succeed, and maybe soon, I will be able to hear the news of your success."
In fact, Professor Tian is not sure whether Lu Li can succeed, he just encourages young people like Lu Li to try boldly.
Lu Li smiled shyly: "Professor Tian, I also think you will hear the news of my success soon."
Professor Tian immediately became happy: "You kid, you are really confident, but it is a good thing to have confidence. Young people should have confidence."
After a pause, he said again: "Do you have anything I can help you with now?"
Lu Li thought for a while and said, "I want to apply to the school for an advanced laboratory for research."
"In addition, I want to apply for some HIV samples and some macrophages."
Professor Tian said immediately: "I and Old Xuhui will apply to the school for your laboratory together. With your current achievements, the problem is not big. The laboratory can apply within three days. As for HIV samples and macrophages, Cells are available in my laboratory. You can go to me directly when the time comes. Do you have any other needs?"
Lu Li shook his head and said with a smile: "These are enough."
Next, the three chatted for a while.
Mainly Professor Tian and Professor Xu asked questions, and Lu Li answered.
However, the discussion is not about academic matters, but about life matters.
Unconsciously, the sky got dark, and Professor Xu let Lu Li leave.
Looking at Lu Li's back, Professor Tian said with a smile: "Old Xu, you really have a good student. You not only have extraordinary talents, but also have a very good personality. Even if you have made achievements that shocked the academic world, Not impetuous at all."
Professor Xu said triumphantly: "I also think he is my most proud student. In front of him, the entire University students. No one can fight."
Professor Tian couldn't help rolling his eyes: "Old Xu, why are you starting to pretend to be coerced? Maybe you are affected by Lu Li. If you want me to say, that kid is good at everything, just likes to pretend to be coerced."
Professor Xu: "…"
Think about it, it really is like this.
When did it start to be affected?
It seems that on the day when he first met Lu Li, he asked Lu Li: "You remember which page of the book is the relevant content, did you memorize the entire book?"
Lu Li replied like this: "I didn't memorize it deliberately. I have the ability to remember it. I only read it once and I can't forget it."
Since then.
Professor Xu felt inexplicably that the fresh and refined way of pretending to be…very cool!
Inadvertently began to imitate.
…
Lu Li returned to the dormitory after eating dinner in the school cafeteria.
I thought it had been a long time since I contacted my parents.
He called home and chatted for a while.
Then, inexplicably, he missed those high school classmates who spoke so nicely.
Open the WeChat group of the experimental class.
I found that my classmates were chatting very happily.
"For this month, I have eaten and lived in Internet cafes. I play games every day when I wake up, and go to sleep when I get tired. It's so cool!"
"Haha, my Yasuo knelt for fifteen consecutive times, and his teammates shed sad tears, calling me a primary school student… I won't tell them that I have passed the University."
"The driver's license has been obtained, and soon, I will become the god of autumn mountains."
"Uuuuu… I watched the news yesterday, and my online dating partner was arrested. It was clearly Loli sound. It turned out to be a thirties-year-old man who squeezed his feet. He practiced Loli sound for a month. I lied to 300,000, including 2,000 of my contribution…"
Seeing this message, Lu Li couldn't help laughing and sent a message: "…"
"Lu Xueshen is here!"
"All stand up and salute the boss!"
"Lu Li, didn't you go to University. After experiencing college life for a while, tell us what is college life like? And ah, I heard that the college sisters are very enthusiastic, isn't it true? "
The WeChat group immediately boiled, because everyone is going to university soon, and they are very interested in university life and want to know in advance.
Lu Li thought for a while and posted a close photo of herself and her senior sister, and added: "This is the senior sister of Yanyi University. Now it is my girlfriend."
classmates:"..."
f*ck, do you want to hit people like this… We are just fantasizing about Senior Sister in our hearts, and you have already taken down Senior Sister, you are still such a beautiful graduating senior, you are going against the sky.
The group was silent for a while.
Everyone said they were very hurt and didn't want to talk.
See here.
Lu Li posted a link again and added: "This is an essay I wrote after I arrived at National Taiwan University, and it was published in the journal Cell. In short, my university life is very fulfilling, my studies are improving, my girlfriend is also found it."
classmates:"..."
You pretend to be a criminal! ! !
You pretended to be so forceful, and you have already caused 10,000 points of critical damage to our hearts!
The group was silent for a while.
But soon, the emoji packs appeared one after another.
The picture is the picture Lu Li just posted, but the senior sister has been replaced, and it has become a flower with nostrils, and there are special effects of ghosts and animals, and then it is accompanied by the text: "This is the senior sister of the University. My girlfriend."
The beauty of the elder sister is pleasing to the eye, and the photo of Lu Li and her elder sister will only make people envious of Lu Li.
But when the senpai was replaced with Ruhua, that scene, the effect… it just exploded.
Lu Li vomited directly.
However, this is only the beginning.
The classmates are super talented, and replaced the senior sisters with King Kong Barbie, Sadako… and even Dashi Johnson.
Lu Li: "…"
Count you very much!
I'll talk to my senior sister!
at this time.
Inside a female dormitory.
Qin Wei sat in front of the computer with a crimson face, staring at the picture on the screen with wide eyes.
Although it was a yardable movie, it still had a great impact on her.
"What are you shy? Now college students, whether they are male or female, have not seen this kind of film. I can guarantee that Lu Li has also watched it. You have never watched it. It is a rare species. "
Zhou Jingjing said calmly.
"This, this…is it really like this?"
Qin Wei squeezed the corners of her clothes with both hands, sweat dripping from her forehead, and said weakly.
"certainly."
Zhou Jingjing promised, patting her chest.
at this time.
Jingle Bell.
Qin Wei's cell phone rang.
Like a guilty conscience, Qin Wei jumped up from her chair in fright, panting, and after a long time she was relieved. He picked up the phone and saw that it was Lu Li's call and quickly turned off the computer. , The phone is connected.
"Senior sister, it's still early, let's go to the cinema to watch a movie."
Lu Li said.
"Watching a movie… Ah, I'm not watching a movie, I'm not watching…"
Qin Wei said in a panic.
"Senior sister? What's the matter with me? I'm not thinking about talking. I'm not watching the movie? Oh… I don't want to go to the movie. Okay, then I'll read the book myself."
Lu Li made up for Qin Wei's meaning and hung up.
"Yeah! If Lu Li knew about it, I wouldn't have the face to meet people!"
Qin Wei stomped her feet in a gesture of a little woman.
"What's the matter?" Zhou Jingjing looked disapproving, "I can guarantee that you will watch this kind of movie with Lu Li in the future, and you will also watch and learn."
"You old dirty girl!"
Qin Wei gave Zhou Jingjing a white look, and then couldn't help but start to make up his mind, and then… the pretty face was as red as a ripe apple.
"Help people to the end, send the Buddha to the west." Zhou Jingjing said with a smile, "Next, I will help you advise on how to get Lu Li as soon as possible."
…
Professor Tian and Professor Xu moved quickly.
the next day.
Lu Li received a call from the school and he has obtained the right to use a GMP-level advanced laboratory.
He quickly called Professor Tian and Professor Xu to express his gratitude, and then came to the laboratory and found that although the laboratory's equipment is not the most advanced, it is enough for him to carry out the experiment.
"Well, it's already pretty good."
Lu Li said he was very satisfied. He was able to obtain the right to use a high-level laboratory without making any contribution to the school. stand up.
However, Lu Li also made a decision to make some money as soon as possible, buy the world's top equipment, and build his own, the world's most advanced biological laboratory.
As for the way to make money…Of course, a cure for AIDS has been developed.
Thinking of this, Lu Li couldn't wait any longer and went directly to Professor Tian's laboratory.
"Xuedi Lu, the teacher is in a meeting at the Academy of Sciences, but he has already told me that I will prepare the things you want."
As soon as Lu Li entered the laboratory, a female doctor with glasses greeted him. While talking, she looked at Lu Li curiously. Her appearance is really high and she can be eaten as a meal. If it weren't for me already. My boyfriend will definitely try to attack him.
"Then trouble Senior Sister."
Lu Li responded politely, and followed the female doctor to the biological cold storage room dedicated to storing the virus.
"The samples of HIV and macrophages you want are here."
While talking, the female doctor opened an aluminum alloy box, which is a reagent box specially used to store biological samples. There are a lot of reagent tubes neatly placed inside, and there are labels on the reagent tubes with corresponding information written on the labels. .
"You fill out this form and you can take the sample away."
At this time, the female doctor spoke again.
Lu Li nodded, filled out the form, and was about to leave with the reagent box. The female doctor said again: "These HIV samples have not been inactivated. You must be careful when you perform the experiment."
The so-called inactivation is the activity of destroying HIV.
There is no danger of inactivated HIV, there is no danger of infection and self-replication.
Normal students use inactivated HIV in their experiments.
But the HIV in Lu Li's hands is not inactivated, that is to say, he may be infected with HIV if he is not careful.
Once such a thing happened to a student, and the whole person fell apart.
"Senior sister, don't worry, I will be careful and careful."
Lu Li said with a smile.
After speaking, he left here and came to his laboratory.
Then, he opened the reagent box and picked up a reagent tube containing an HIV sample.
"This is HIV?"
Lu Li looked at the liquid in the reagent tube indifferently, and a series of messages appeared in his mind.
HIV, also known as human immunodeficiency virus,HIV infection in humans came from a type of chimpanzee from Central Africa.
The chimpanzee version of the virus (called simian immunodeficiency virus, or SIV) may have been transmitted to humans when chimps were hunted for their meat and came into contact with infected blood.
Studies show that HIV may have passed from chimpanzees to humans as early as the late 1800s. was first discovered in America in 1981 and then quickly spread to the world. 32 million people have died of AIDS, and the number of existing AIDS patients has reached a terrifying 40 million. , All mankind is terrified like a tiger.
However, Lu Li looked at the HIV sample in front of him. Not only was he not scared at all, he was a little bit happy.
"HIV, come on."
Lu Li removes a straw from the shelf on the side table, draws a drop of liquid from the reagent tube containing the HIV sample, and then drips it on his left index finger, and then uses a blade to gently place it on his left index finger. It made a small wound, and the bright red blood immediately flowed out.
This is because AIDS is transmitted through sexual contact, blood transmission, and mother-to-child transmission.
He needs to create a bleeding wound to allow HIV to enter his body.
"If others see this scene, they will treat me as a lunatic."
Lu Li smiled. *
Walking out of the laboratory, Lu Li picked up the phone again and opened the WeChat.
I haven't read the WeChat news for two weeks. Just when I opened it, I saw that the screen was full of unread messages.
There are members of the experimental class WeChat group, classmates, parents, and sister Qin Wei.
Lu Li first clicked on the message sent by the senior sister, and probably browsed through it, only to find that the senior sister would send him messages every day.
The latest information was sent last night.
There are three lines in this message.
First line: U/R
The second line: 1000mL, O2/2, m/ρ, F/q
The third line: kx+b, O2/2, radical PR
Seeing this message, Lu Li smiled knowingly.
Because he could see the hidden meaning of this message at a glance.
The first line is Ohm's law: U/R=I
The second line: 1000ml=1L, O2/2=O, m/ρ=V (mass/density=volume), F/q=E (electric field strength formula)
The third line: kx+b=Y (linear function), O2/2=O, radical PR=U (relationship between electric power and voltage resistance)
So, these three lines add up to: ILOVEYOU.
"Senior Sister is so interesting. I haven't been with Senior Sister for so long, so I have to spend a good time with her today."
A smile was drawn at the corner of Lu Li's mouth and he dialed the senior sister's phone. After the call was connected, he said directly: "Senior sister, I have already left the laboratory. I will leave it to you today. I want to go. Anything will do."
"Great, then I will come to you now."
The senior sister said happily, and was silent for a moment, and then stammered: "I…I want to go to the movies."
"Watching a movie? Of course no problem, I will go back to the dormitory to change my clothes, and then go with you."
Lu Li said with a smile.
The two chatted for a while, and then hung up.
Lu Li went directly to the dormitory.
The elder sister didn't know what she thought of, her body was tight, her face was red like an apple.
After Lu Li returned to the dormitory, he took a shower, shaved his beard, and then changed into new clothes.
The appearance returns to perfect state in an instant.
When I came to the outside of the dormitory, I saw the senior sister.
"Senior sister, why do you look something wrong? Are you feeling unwell?"
Lu Li glanced at the senior sister, and then cared about the problem.
"No, I just didn't get a good rest."
The senior sister quickly denied that she was in good health, but she was a little shy and nervous thinking about what would happen next.
Lu Li didn't think too much, and walked out of school directly with the senior sister.
First, I sorted out a hair, and then went to the movies with my senior sister.
I used to watch a movie when I watched a movie with my elder sister, but today, my elder sister seemed to want to watch the movie. She watched two movies in a row. When I left the cinema, it was already 6 o'clock in the afternoon, which happened to be At dinner time, the two found a private kitchen.
"Senior sister, after playing for so long, are you tired? Do you want to go back to school?"
After eating, Lu Li suggested.
"I…I'm not tired, I want to buy some clothes."
Senior sister said quickly.
"Then go buy clothes, just right, I also want to buy some clothes."
Lu Li nodded.
The two came to the mall and walked around… it was just after 11 o'clock. However, Lu Li didn't check the time, but felt a little hungry. It just so happened that the senior sister offered to have a barbecue at this time.
Lu Li nodded immediately.
When I came to the barbecue stall, was full of food and drink, and was about to leave, the senior sister suddenly said, "Huh? Why is it so late? It's already twelve o'clock, and the school dormitory is no longer allowed."
Lu Li took out his mobile phone to check the time, then recalled what happened today, and suddenly wanted to understand what the senior sister was making.
He immediately said: "It's okay. It's fine to stay in the hotel tonight. It's the off-season. There must be a lot of vacant rooms in the hotel. If we open two rooms, I will live next door to you. If I get into trouble, I can come as soon as possible. help you."
Senior sister: "…"
This is different from what I thought.
Shouldn't it be only one room?
If I open two rooms, won't my plan fall into frustration again? Zhou Jingjing must be laughing to death. Two consecutive attempts to pluck up the courage to take down Lu Li failed.
The elder sister couldn't help but stomped her foot, but she was embarrassed to say what she was thinking. She wanted to post a question on Zhihu: "Now I'm going to the hotel with my boyfriend, but my boyfriend said that he wants to open two rooms. Does he only open one room? Wait online, hurry!"
Lu Li looked at the tangled senior sister, directly took her hand, clasped her five fingers, and smirked: "It was just teasing you. You have done it so obviously. If I still can't see you I'm too stupid."
the next day.
It was ten o'clock in the morning.
Lu Li just woke up, yawned, and then looked at the delicate face of the senior sister beside him, a sense of satisfaction suddenly rose in his heart.
This is the real day.
However, it is time to buy a house. It is too inconvenient to stay in hotels and schools. *
Lu Li and Qin Wei-senpai left the hotel, and when they returned to school, they separated.
Qin Wei bought something and returned to the dormitory. As soon as she walked into the dormitory, she was discovered by Zhou Jingjing.
Zhou Jingjing gave a smirk: "Tsk tsk, where did someone go last night, did he do something bad?"
Qin Wei didn't know what she thought of, her face flushed.
By this time, Lu Li had already arrived in the laboratory.
It's time to be busy after being cool for so long.
The matter is also very simple, nothing more than the use of single-base gene editing technology to edit the genes of macrophages.
He already has the correct genetic code, and the next job is equivalent to copying homework.
However, when Lu Li took out the macrophages from the reagent tube and observed them with a microscope, they found that these macrophages had died.
"I almost forgot. The life cycle of macrophages is only two to three weeks. I received the sample more than ten days ago. Calculating the time, it is almost the same."
Lu Li murmured, then contacted Professor Tian and went to Professor Tian's laboratory to apply for some HIV samples and macrophage samples.
Next, Lu Li got busy in the laboratory.
Although using single-base gene editing technology to perform gene editing is much less efficient than using a cell editor, he doesn't need to study now, just copy homework, and the speed is still very fast.
Ten hours later.
Lu Li has transformed thousands of macrophages. He calls these macrophages "new macrophages" and divides these new macrophages into twelve groups, which are placed in ten petri dishes.
Under the electron microscope, they are no different from the original macrophages, but theoretically, they can recognize and destroy HIV, as well as cells infected with HIV.
The actual effect will be known only through experiments.
"Well, put in some HIV and try it."
Lu Li carefully put the HIV virus into the ten petri dishes and observed them carefully.
Through an electron microscope, Lu Li found that these new macrophages did not disappoint him at all. When they encountered HIV, they would actively rush up and then begin to swallow them. The direct macrophages are about 60 microns in size. The largest cell in the human body, and the diameter of HIV is only about 120 nanometers (1 micron = 1000 nanometers). Therefore, macrophages eat up HIV, just like a shark eating dried shrimps, one bite by one, crunchy and crisp.
In a short while, a new macrophage swallowed dozens of HIV under Lu Li's gaze.
Seeing this scene, Lu Li was a little excited, because it means that the experiment has been half successful. Next, as long as the new macrophages can break down the eaten HIV, the experiment will be successful.
Generally speaking, after HIV enters the macrophages, it only takes 4 to 6 minutes to kill the macrophages and then emerge from the macrophages.
So, if after 6 minutes, this new macrophage is still alive, it means that it has probably broken down the HIV that was eaten by it.
Lu Li waited patiently.
1 minute.
2 minutes.
6 minutes.
10 minutes.
"Very well, this new macrophage is still alive, and no HIV emerges from it."
Lu Li looked very excited all over.
However, the experiment is not over, he will also cut open this new macrophage to take a look at the inside of the cell.
"There is no HIV inside the cell, which means that HIV has been broken down! This new macrophage can beat HIV!"
After seeing the inside of the new macrophages through the electron microscope, Lu Li was in a good mood, but now it was past 11 o'clock in the evening, and he was also a little tired, so he returned to the dormitory and ate a bowl of soak. Face, then began to rest.
After waking up the next day, he hurried to the laboratory again to continue the experiment.
He also needs to determine whether the new macrophages can swallow and destroy the cells infected by HIV.
Six hours later.
Lu Li watched the HIV in the petri dish and the HIV-infected T cells, all being swallowed and destroyed by the new macrophages, and couldn't help feeling surging.
From this moment on, he can tell the world loudly: "I, Lu Li, have overcome AIDS!"
He can completely imagine that once the news is released, the whole world will be shocked. The AIDS, which has always trapped countless scientists around the world, has been helpless by scientists, and has been found a cure!
Not only that, this method and idea can also be used to treat other diseases, such as cancer. Macrophages can also swallow cancer cells.
If single-base gene editing technology is used, the genes of macrophages can be modified to make macrophages. Phages can recognize and destroy cancer cells, and the cancer will naturally be cured.
There is no doubt that this is definitely a super event that is enough to attract global attention.
However, at this moment, Lu Li suddenly thought of a question.
His method of treating AIDS is completely different from traditional medicines. The current medicines are basically chemicals that are difficult to imitate, but what he uses to treat HIV is new macrophages, which can divide.
As long as you get a sample, you can produce unlimitedly, even only an ordinary college student who understands biology, plus a small laboratory, can produce.
This also means that he may only gain fame, but not make money.
As for the registration of a patent? This is also not very reliable. Nowadays, pharmaceutical patents are very common, but people just ignore them. Generic drugs are everywhere and are even delivered to the world.
What's more, there are nearly 40 million AIDS patients in the world. What a huge market! At that time, even in other countries, there will be countless people making generic drugs for money, and there is no way to stop it!
"Can I only earn a reputation?"
Lu Li muttered to himself.
He is a little unwilling.
He also lacks money. He wants to build his own top-notch laboratory. He wants to buy a house and a car. He wants to let himself and his family live a life without bad money.
"This money is what I should earn, and I must protect my own interests."
After Lu Li made the decision, he began to think hard. Suddenly, his eyes lit up and he said excitedly: "The genetic technology I have mastered can completely solve this problem."