They never got along well from the start, and his character is an utter contrast to hers which paved no way for them to understand each other.
Sargon didn't let her stay in the palace when they had a big arguement and that's the first time he hit her which ended up Lila having a miscarriage. He sent her away to this forest. There's no one here to help her, she has to cook, clean and cultivate her own food. On top of that she isn't allowed to leave. Lila thought he abandoned her, but Sargon showed up after a month, during which they reconciled and she decided to give him a chance. Either she can die or be his wife, that's all the option she had.