At this point, Francis was already fed up with Joe Statman's appearances. It wasn't the fact, that he was strong, or anything like that, no, it was his sheer persistence, his will to never give up, and try to fight Dan. Now, for some reason, Francis has been the one person who has dealt with him, and even at this point, his attention once again has to fall on this man.
Was it hard to deal with him? No, not particularly. Francis has been way stronger than Statman, even when they were still in prison, after all, all it took for him, was a well placed blow, and he was out. Or at least somewhere far away. The only thought that remained in Francis after each of these battles, is just a simple why. Why was he still so hellbent on fighting them? Didn't he already learn his lesson?