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The Fragment of the Red Orb was what the Flame Emperor had used as the core of Pandemonium's body through his resurrection. After having gathered all the fragments within the continent, he complemented the missing body parts using the body parts of old fire dragon corpses, and with the Red Orb Fragment and its fiery divine powers, he unified everything together into the current Pandemonium, reviving him.
And at the moment, Drake had taken away that core of his own body, causing several defects to rapidly appear through his demonic body, he felt weaker, slower, and strange. Although he wasn't falling into pieces as he had imagined before. After unleashing several evolutions and awakenings of his base body, Pandemonium had been able to recreate and strengthen his physical form to the point it wasn't just a Frankenstein abomination anymore.
