Loss, if not managed properly, breeds hatred. If left unattended, the tiny spark of destructive negativity can burgeon out of control and consume the person completely from within. It starts with hatred of the circumstance - "why must I be subjected to this loss?"
Losing a loved one, losing an opportunity, or losing anything hard-won, automatically causes the one experiencing the loss to begrudge the immediate cause, which is the direct entity that caused it.