When Dondochakka and Pesche's Cero Sincretico fails, Szayelaporro Granz explained that he had already predicted that they could create such an attack. Since they were now out of tricks, he will put an end to everything. Then suddenly a Shinigami wearing captain's clothes accompanied by a female Shinigami arrived at the scene. Captain painted his face black and white, wore a strange golden thing around his face as well as golden colored teeth. He was Mayuri Kurotsuchi, the captain of the 12th division of Gotei 13.
As Mayuri Kurotsuchi arrived Szayelaporro his name but then decided that he won't need it since Mayuri was another being that will be erased by him.
Mayuri upon hearing this he insisted that he must know Szayelaporro's name so that he would be able to properly label him when he bottles him up.
Szayelaporro used the same trick he used on Renji and Uryu as he 'ate' Mayuri with his tentacle-like things. Soon the Mayuri was spat out from the cocoon.
Szayelaporro was holding a doll of Mayuri and as he was breaking body parts, he told Mayuri that it was sad that a captain level Shinigami could do nothing against his abilities.
Mayuri began coughing up blood and Lieutenant Nemu Kurotsuchi, who came with Mayuri as well, watched the battle from the sidelines.
Szayelaporro stated that his appearance was just for show like he thought, but Mayuri got up as if nothing happened and said "Yeah right." while making a funny face.
Szayelaporro was surprised at first then decided to destroy more of his body parts, but it did nothing and Mayuri asked for Nemu to come over to him.
Szayelaporro dropped the doll he was holding and angrily smashed it to pieces. He then asked Mayuri what ability he has, but Mayuri told him that he doesn't have anything like that and stated that he put bacteria on Uryu for surveillance purposes, which allowed him to replace all of his body parts with dummies.
However, Szayelaporro pointed out that it should be impossible to do that since he just revealed his ability less than an hour ago, but Mayuri countered him by saying that if it were impossible, then he shouldn't be standing here right now.
Uryu interrupted their conversation and complained about everything wrong with putting bacteria on him for surveillance purposes, but Mayuri simply told him to be quiet.
All of a sudden, Nemu was grabbed by Szayelaporro's tentacle and he told Mayuri that he was a fool for letting his underling get captured, but Nemu told him that capturing her doesn't make her a hostage.
Szayelaporro began arguing with her and Mayuri was annoyed by all the noise going on. Mayuri decided to activate his Bankai, Konjiki Ashisogi Jizo. Then Mayuri's Zanpakuto disappears and materializing a big golden baby faced worm thing wearing a red cape. Then it released a poisonous gas into the air. Szayelaporro attempted to counter this, but it was too late as the Bankai crushes him.
Mayuri could faintly hear the battle going on between Kenpachi Zaraki and Nnoitra Gilga.
Mayuri's Bankai then got up and Renji noted that it was eating Szayelaporro.
Lieutenant Renji Abarai was then affected by the poison that has just been released and he asked Uryu why he was fine. Uryu replied that he must have formed antibodies since he encountered this poison before. He then asked Mayuri for the antidote, but just then he too was affected by the poison. Mayuri told him that he wouldn't be a scientist if he didn't always change his poison, and he stated that something like antibodies would never stop him. Uryu told him that he got that he's a genius and simply asked for him to hand over the antidote.
Nemu, who was being held by Mayuri's Bankai, asked if she could be let down, but Mayuri simply ignored her. Uryu told him to let her down, but he still ignored this request but decided that he will give them the antidote and threw it to them.
All of a sudden, Nemu began screaming in pain, and Uryu pleaded with Mayuri to let her go.
Szayelaporro's voice then appeared and he stated that it's going to take much more than that to defeat him. He then told them that they were going to bear witness to his greatest ability, Gabriel, which allows him to asexually reproduce within the womb of his prey and that soon his host will become nothing more than an empty shell. He then left out of Nemu's body and said that the only downside to this is that it ruins his hair.
Szayelaporro explained to Mayuri that he will always be able to resurrect himself and that death has only become another part of his life cycle, making him the perfect being. He told Mayuri that no matter what he does there was no way for him to win.
Mayuri simply walked past Szayelaporro and went up to Nemu.
Szayelaporro thought that Mayuri was saddened to see his subordinate dying, but Mayuri simply smiled at him and said he has an interesting ability. He then mocked Szayelaporro asking if that's all he can do and Szayelaporro had Konjiki Ashisogi Jizo attempt to eat Mayuri.
He explained to Mayuri that when he was eaten by his Zanpakuto he was able to control its nerves from the inside, giving him complete control over it.
All of a sudden, the Bankai blew up and Mayuri told him he would never allow a tool of his to turn on him. He explained to Szayelaporro that he made it so that if it ever betrayed him it would blow up immediately.
Mayuri told Szayelaporro that he was going to use him as a test subject for a new drug of his.
Szayelaporro then got into a battle stance and Mayuri told him that there was no need as the "drug" had already taken effect. He explained to him that if anyone were to eat or invade Nemu's body they would be affected by one of several drugs placed in her body. From the area of her body through which Szayelaporro exited her, he had been affected by what Mayuri calls the Superhuman Drug. He told him that he had acquired superhuman senses and everything should feel as if it's going incredibly slow right now and asked if it looks like his blade has stopped. Mayuri then told him that one second should feel like a century because his non-superhuman body will fall terribly behind his superhuman senses, causing the movements of his flesh to be left behind.
Mayuri then stabbed Szayelaporro's hand and said that the pain should last for over a hundred years. He continued bringing his Zanpakuto closer to Szayelaporro's heart as he looks on in fright.
Soon the Zanpakuto then went through him and Szayelaporro Granz died wondering how many years has been since the sword first inflected on him.