A single Ming Luo Fruit had raised Ning Fan's mental state cultivation base by fifty years. However, he didn't continue eating the rest of the Ming Luo Fruits after that.
His present mental state had already reached the peak of Harmonious Spirit realm, which was in line with his current cultivation base. If he went further, it would be Gold Core realm, the time when he had to confront the Heart Devil.
If that was the case, he could only take another Ming Luo Fruit again if he really formed his core.