In the Diablo world, Sanctuary, the High Heavens, and the Burning Hells were physically isolated from each other. The High Heavens and the Burning Hells belonged to different Purgatory Spaces, while Sanctuary was hidden in the gap between the two.
But because of the existence of portals, these three places were connected in spatial concepts. In other words, in theory, the mortals of Sanctuary could go to the High Heavens and the Burning Hells.
However, in the thousands of years of Sanctuary's history, there were very few rumors about the High Heavens and the Burning Hells. The description of these places was only a general concept.
If the High Heavens forbade mortals to enter because of the pride of angels and their disdain for mortals, then the Burning Hells forbade weak mortals from entering because of the cruel and terrifying environment.