As soon as Sam saw what was inside this transparent barrier. A blue-colored heart which looked like a human heart beating under the transparent barrier, pumping a blue-colored liquid into the surrounding soil.
This is extremely similar to the Sesh's heart he found when he went to find the meteorite sand island and then it also reminded him of that large pillar competition ground and then the guardian.
To this day, he doesn't know if Sesh's heart placed under the sea which created a poison zone in the sea was related to the guardian. But he sure as hell knew that both hearts are related.
As soon as he saw this, he got the many answers he needed. The mutation might have been caused by the blue liquid that was circulating and if his guess was right, it is demon blood and it affected the entire ecosystem and mutated every living being, and this guy whoever that made this possible might just be a person who is interested in experimenting with different species.