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After Kireina left and ended ignoring Frank's request, he felt slightly heartbroken.
But at the same time, he seemed to have regained some hope as well, and learned a couple of things.
One of them is that he had to simply "keep living his best life" and continue moving forward with whatever life throws at him.
Kireina definitely knew more about this, but it seemed she was risking her own existence or something if she were to talk about it.
So she ended remaining quite cryptic, although she gave him a few hints at the end.
"Go to the Corrupted Domains, any that appears in this city, you'll unravel the truth as you fight for your life."
It seemed that directly intervening wasn't her way of doing things, and with the memories/dreams of what he knew about her, Frank could deduce this might be her own way to help him.
Whatever was going on in Tokyo, the Corrupted Domains could be the key for him to learn more about "the truth".
