Well, humanity has long changed from what it used to be.
During this time, Hertfilia discovered a potion that will mutate human genetics, allowing everyone to live up to 200 years old.
Now, at the age of 50, people look like they are 25. They also found that they awakened innate gene abilities that were ranked from E to A, and above A were S classes.
Humans became swifter, stronger and faster, which helped when facing a wide range of alien invaders.
Another 5 years later, the Human Alliance is formed, and Humans are officially accepted into the Galactic books by Alien species who saw them as only food, toys, or slaves.
Humans now have a collection of 170 planets, livable and non-livable under their grasp.
People in Prison like Whitebeard who refused to change, found that they were transported to an entire planet called Prison planet.
