5th floor of the spire.
"Run! This guy is not easily taken down! We need to call the others upstairs to help-" before one of the guys can escape, I already shot him down with the Versatile Weapon, killing him before he can even go upstairs and ask for some backup.
I didn't have much difficulty with them all as they are not as difficult as monsters. One shot in the head or one stab in their body and they are dead so defeating them is much easier compared to the monsters that take a longer beating before they are officially declared killed.