One's emotions and living environment would be a great influence on any disease, especially autoimmune diseases. Although there was no data which could display how important the emotions and living environment were, these factors would indeed affect the patient's desire to live as well as cooperation with treatment.
An autoimmune disease would start spreading very swiftly once the patient lost the desire to live or lost hope for the future. Even medical treatment might become no longer effective in that scenario.
After Wang Yan was diagnosed to have systemic lupus erythematosus, not only did her husband not console her, he even demanded a divorce. This only served to pour fuel on the fire, cutting off her hope for the future—a truly heartless move by her husband.