Where was the first metatarsophalangeal joint? It was actually quite simple: the point where the big toe was connected to the foot was where this joint was. On the hand, the thumb's functions were the most numerous and most important. It was the same for the big toe of the foot as this joint was a highly active one.
People who injured the first metatarsophalangeal joint were either fat or professional sports athletes. People who were fat would cause the joint to suffer too much pressure from the weight, while athletes would typically suffer sports-related injuries. However, there was also one group of normal people who weren't overweight that would often injure this joint: women who really liked to wear high heels, especially the really tall high heels. Although such high heels would make them seem tall and beautiful, the tall high heels were really good at destroying the metatarsophalangeal joints.