As for the issue regarding if the genetic lock really existed and could be open…
In fact, after Mr. Fang got strengthened by the T-Virus, he found that his physical strength and reaction speed had greatly improved.
Even though these benefits were similar to those of the genetic lock, one couldn't say that genetic locks existed and could be opened. One could only say that these benefits came from the T-Virus itself.
Mr. Fang didn't know if the genetic lock could be opened or not, but he knew that he hadn't figured it out yet.
However, regarding the question if people could unleash their potential during danger, there were many examples showing that people could indeed unleash great potential during dangerous situations and under great pressure.
While Helen began playing Resident Evil 2, Mr. Fang suddenly remembered his dream.